Tesis doctoral de Marta Mele Messeguer
The aim of this work is to use the information left by recombination in our genomes to make inferences on the recent evolutionary history of human populations. For that, a novel method called iris has been developed that allows detecting specific past recombination events in a set of extant sequences. Iris is extensively validated and studied in whole set of different scenarios in order to assess its performance. Once recombination events are detected, they can be used as genetic markers to study the recombinational diversity patterns of human populations. We apply this innovative approach to a whole set of different human populations within the old world that were specifically genotyped for this end and we provide new insights in the recent human evolutionary history of our species.
Datos académicos de la tesis doctoral «Incorporating recombination into the study of recent human evolutionary history«
- Título de la tesis: Incorporating recombination into the study of recent human evolutionary history
- Autor: Marta Mele Messeguer
- Universidad: Pompeu fabra
- Fecha de lectura de la tesis: 29/03/2011
Dirección y tribunal
- Director de la tesis
- Jaume Bertranpetit Busquets
- Tribunal
- Presidente del tribunal: julio Antonio Rozas liras
- chris Tyler-smith (vocal)
- (vocal)
- (vocal)