Tesis doctoral de Beatriz Apellaniz Unzalu
1- relevant in vitro assays for mper membrane activity should include:- mper peptide redefined to bear the hydrophobic-at-interface region plus the nterminalresidues of the tmd.- A lipid bilayer whose composition includes concentrations of cholesterol as highas those present in the viral envelope.2- preliminary results support that in vitro assays for mper activity, optimizedaccording to those parameters, are useful tools for new hiv-1 inhibitor and immunogendevelopment.
Datos académicos de la tesis doctoral «Functional and structural characterization of peptides derived from hiv-1 gp41 membrane proximal and transmembrane domains. implications for anti-hiv inhibitor and inmunogen development«
- Título de la tesis: Functional and structural characterization of peptides derived from hiv-1 gp41 membrane proximal and transmembrane domains. implications for anti-hiv inhibitor and inmunogen development
- Autor: Beatriz Apellaniz Unzalu
- Universidad: País vasco/euskal herriko unibertsitatea
- Fecha de lectura de la tesis: 11/06/2012
Dirección y tribunal
- Director de la tesis
- José Luis Nieva Escadón
- Tribunal
- Presidente del tribunal: Jesús Perez gil
- enrique Perez paya (vocal)
- jamie k. Scott (vocal)
- gorka Basañez asua (vocal)