Tesis doctoral de Catalina Ana Rossello Castillo
Organism. Blood cell production is sustained throughout the life of an organism by a population of self-renewing multipotent hematopoietic stem cells (hscs). There are three hallmark characteristics of the hscs: ability for self-renew, potential to differentiate into all hematopoietic lineages, and capacity for long-term reconstitution (ltr) of the hematopoietic system when transplanted into lethally irradiated recipients. vertebrate hematopoiesis is thought to occur in two successive waves, primitive and definitive, which differ in the cell types produced and their anatomic location. Whereas the primitive wave occurs transiently and produces only certain blood lineages, the definitive program continues throughout the whole lifespan and produces hscs capable of giving rise to all blood lineages (rev. In galloway et al., 2003).
Datos académicos de la tesis doctoral «Role of the homeobox gene meis 1 in hematopoietic stem cell generation in the vertebrate embryo: a functional analysis«
- Título de la tesis: Role of the homeobox gene meis 1 in hematopoietic stem cell generation in the vertebrate embryo: a functional analysis
- Autor: Catalina Ana Rossello Castillo
- Universidad: Autónoma de Madrid
- Fecha de lectura de la tesis: 02/12/2009
Dirección y tribunal
- Director de la tesis
- Miguel Angel Torres Sanchez
- Tribunal
- Presidente del tribunal: federico Mayor menendez
- anna Bigas salvans (vocal)
- nadia Mercader huber (vocal)
- daniela Piazzolla (vocal)