Tesis doctoral de Neus Gomez Bastus
The tremendous achievements ¡n nanotechnology over the last few years have been closely related to a growing understanding of various physical and chemical processes that make nanometer scales different from both macroscopic scales and atí²mic scales. As challenging as this is, nanoparticles and macromolecules enable a substantially greater ability of control than í toms as building blocks for new materials and thus are well positioned to contribute significantly to new materials. The diversity of components and processes leads to the recognition of the critical role of cross-disciplinary research, including not only that between traditionally different áreas within chemistry, but also between chemistry and biochemistry, physics, and a number of engineering disciplines. in this thesis we address the design of nanoparticles conjugates for biomedical applications.The interdisciplinary character of this freíd implies the synthesis (control of the size and shape), conjugation (peptide, proteins and drugs), stabilization (charges and steric), characterization (physico-chemical and structural) and the study of the properties (optical, thermal) of the nanoparticles for their final use in as biomedical agents. These biológica! Applications include the use of gold nanoparticles as local and remote entities to manipúlate protein aggregates and the macrophage activation towards peptide-conjugated gold nanoparticles.
Datos académicos de la tesis doctoral «Gola nanopartícles for biomedical applications: synthesis, conjugation and «in vitro» experiments«
- Título de la tesis: Gola nanopartícles for biomedical applications: synthesis, conjugation and «in vitro» experiments
- Autor: Neus Gomez Bastus
- Universidad: Barcelona
- Fecha de lectura de la tesis: 17/12/2008
Dirección y tribunal
- Director de la tesis
- Victor Franco Puntes
- Tribunal
- Presidente del tribunal: horst Weller
- María del puerto Morales herrero (vocal)
- Luis Manuel Liz marzan (vocal)
- isaac Ojea jimenez (vocal)