Tesis doctoral de Iván Efraín Martínez Forero
The objective of this thesis is to improve the understanding of chemical reaction networks derived from signaling pathways of biological interest. To this end, we make a study of the ordinary differential equations that model the dynamics of the chemical species participating in the network. We put a special emphasis in equilibrium solutions of the system applying methods from algebraic geometry and convex analysis. The techniques developed are used in the study of biological systems of interest such as apoptosis and interferon beta signaling pathway which are involved in human complex diseases (cancer and multiple sclerosis).
Datos académicos de la tesis doctoral «Reaction network analysis in biochemical signaling pathways«
- Título de la tesis: Reaction network analysis in biochemical signaling pathways
- Autor: Iván Efraín Martínez Forero
- Universidad: Navarra
- Fecha de lectura de la tesis: 26/09/2009
Dirección y tribunal
- Director de la tesis
- Antonio Peláez López
- Tribunal
- Presidente del tribunal: Marta Cascante serratosa
- jordi García ojalvo (vocal)
- blas Echebarria domínguez (vocal)
- henar Herrero sanz (vocal)