Tesis doctoral de Eva María Alvarez Moya
English summary (original language) background: the present study starts from a non-genetic high-risk approach to the study of vulnerability markers for schizophrenia spectrum disorders. aims: a) to explore prospectively the relationship between the presence of sustained attention deficit in early adolescence, and exophenotypical measures of vulnerability to schizophrenia spectrum disorders (neurocognitive, neurointegrative, personality and psychosocial factors) in early adulthood; b) to identify and describe different subgroups of subjects according to their profile of attentional development through adolescence; and c) to explore cross-sectional associations between psychometric schizotypy and some endophenotypical variables (neurocognitive factors). methods: two cohorts of community adolescents were selected in 1993 (phase i) according to the presence (n=301 index subjects) or absence (n=300 control subjects) of a sustained attention deficit, as measured by the continuous performance test. Both cohorts were re-assessed in 1997-98 (phase ii) and 2001-03 (phase iii) with a battery of neuropsychological and personality tests. The last phase (phase iii) was the focus of the present study. In phase iii, attrition reduced the sample to n=42 index subjects, and n=38 control subjects. Both cohorts were administered several measures of neuropsychological functions, psychometric schizotypy, social behavior, coping strategies, personality disorders, and previous general adjustment. The cohorts were adjusted for gender, years of education and age. T-tests and ancova tests were used to compare both cohorts (adjusting for education when needed). Cluster analyses were applied by using attentional performance in all three phases as the main variable. Ancova tests were used to compare the identified clusters among them in all phase iii measures. In addition, pearson correlations were used to correlate psychometric schizotypy with neurocognitive variables. results: index sub
Datos académicos de la tesis doctoral «A 10-year longitudinal study of sustained attention across adolescence in a community sample: psychopathological, personality and biobehavioural correlates.«
- Título de la tesis: A 10-year longitudinal study of sustained attention across adolescence in a community sample: psychopathological, personality and biobehavioural correlates.
- Autor: Eva María Alvarez Moya
- Universidad: Autónoma de barcelona
- Fecha de lectura de la tesis: 22/10/2004
Dirección y tribunal
- Director de la tesis
- Jordi Obiols Llandrich
- Tribunal
- Presidente del tribunal: marco Battaglia
- anabel Martínez aran (vocal)
- Rafael Penadés rubio (vocal)
- josep María Haro abad (vocal)