Tesis doctoral de Jorge Dorado Perez
In this work we have analyzed the antitumorigenic mechanisms of action of the peroxisome proliferator-activated receptor gamma (ppargamma) ligands 15-deoxi-12,14-prostaglandin j2 , rosiglitazone and pioglitazone on human breast cancer cells. Our data show that treatment with these compounds reduces cell viability, induces inhibition of proliferation and promotes apoptosis in several breast carcinoma cell lines, and attribute for the first time similar effects to members of the thiadiazolidinones (tdzds) family of compounds.
Datos académicos de la tesis doctoral «Antitumorigenic mechanisms of action of peroxisome proliferator-activated gamma (ppargamma) ligands in breast cancer«
- Título de la tesis: Antitumorigenic mechanisms of action of peroxisome proliferator-activated gamma (ppargamma) ligands in breast cancer
- Autor: Jorge Dorado Perez
- Universidad: Autónoma de Madrid
- Fecha de lectura de la tesis: 20/11/2009
Dirección y tribunal
- Director de la tesis
- Ana María Pérez Castillo
- Tribunal
- Presidente del tribunal: pilar Santisteban sanz
- Jorge Martin perez (vocal)
- gregorio angel Santos montes (vocal)
- rosario Perona abellon (vocal)