Tesis doctoral de María Grau Magaña
The coexistence of low ami incidence levels and high cardiovascular risk factor prevalence represents the so-called southern europe paradox. When this paradox was described, acute myocardial infarction incidence in spain was between one-half and one-fourth that found in north, east, and west european countries, the usa, and other english-speaking countries. Essentially, the results of the present study found no overall change in acute myocardial infarction incidence in girona over the past decade. Nonetheless, men under age 65, bout half the total acute myocardial infarction population register cases, showed a significant reduction in incidence rates between 1990 and 1999, while the trend in men age 65-74 did not change significantly. The prevalence of risk factors in the girona population was surprisingly similar to those countries with high acute myocardial infarction incidence. In addition, the major cardiovascular risk factors are present in more than 95% of ischemic heart disease cases registered in girona. The prevalence of cardiovascular risk factors, however, has undergone considerable change from the first cross- sectional study organized in this area in 1995 to the 2000 and 2005 studies. The most noteworthy aspects are improvements in participants awareness, control and treatment of hypertension, and improvement in total and low-density lipoprotein (ldl) cholesterol distribution. definitively, primary prevention must be adapted to local characteristics of cardiovascular risk factor prevalence, acute myocardial infarction mortality and incidence rates, and economic and cultural factors. The estimation of population attributable fractions, which represents an important link between causality and public health action, provides relevant information for such adaptation. The population attributable fractions estimates in girona showed that ldl cholesterol levels had the highest potential for ischemic heart disease prevention in people aged 35 to 74 years, along with history of smoking for those younger than 55, and hypertension and high-density lipoprotein cholesterol for those age 55 and older. However, we observed that the population attributable fractions may require periodic recalculation in different age groups to adequately monitor the population trends in world regions.
Datos académicos de la tesis doctoral «Trends in acute myocardial infarction incidence and cardiovascular risk factors prevalence in 6 counties of girona, spain (1990-2005)«
- Título de la tesis: Trends in acute myocardial infarction incidence and cardiovascular risk factors prevalence in 6 counties of girona, spain (1990-2005)
- Autor: María Grau Magaña
- Universidad: Autónoma de barcelona
- Fecha de lectura de la tesis: 03/09/2009
Dirección y tribunal
- Director de la tesis
- Jaume Marrugat De La Iglesia
- Tribunal
- Presidente del tribunal: ramon Brugada terradellas
- veiko Salomaa (vocal)
- (vocal)
- (vocal)